دولة حبشیة فى الیمن – دولة بنی نجاح (412-554هـ) (1021-1159م)

Dmd056614 1016..1021

During preclinical and early phase clinical studies of drug candidates, exposure to metabolites should be monitored to determine whether safety conclusions drawn from studies in animals can be extrapolated to humans. Metabolites accounting for more than 10% of total exposure to drug-related material (DRM) in humans are of regulatory concern, and for any such metabolites, adequate exposure shoul...

A 1021 Paul

NETS 412 : Algorithmic Game

Recall that we argued last lecture that in any game, if every player plays according to the polynomial weights algorithm, then their empirical play history will converge to a coarse correlated equilibrium very quickly. In this lecture, we will give a new learning algorithm such that if every player plays according to it (in any game!) their empirical play history will converge to a correlated e...

Op-brhe120233 411..412

RA is common and costly for individuals, health services and societies. Current guidelines for the management of RA highlight the importance of early administration of DMARDs and the titration of therapy against disease activity to try and achieve remission. Reasonable evidence exists to show that early institution of DMARDs reduces the rate of progression of radiological damage in the long ter...

Pns1300124 412..419

Non-alcoholic fatty liver disease (NAFLD) is now recognised as the hepatic component of metabolic syndrome (MetS). NAFLD is an example of ectopic fat accumulation in a visceral organ that causes organ-specific disease, and affects risk of other related diseases such as type 2 diabetes and CVD. NAFLD is a spectrum of fat-associated liver conditions that can culminate in end stage liver disease, ...